Webinar - The dialog between target tissues and the immune system in type 1 diabetes and other autoimmune disease
Autoimmune diseases are usually studied with focus on the immune system, and less attention is paid to the responses of target tissues exposed to the immune assault.
Recent data suggest that the dialogue between invading immune cells and the target cells may be crucial for the triggering and progression of at least one autoimmune disease, type 1 diabetes.
We evaluated, based on available RNA sequencing data, whether inflammation induces similar molecular signatures at the target tissues in type 1 diabetes, systemic lupus erythematosus, multiple sclerosis and rheumatoid arthritis. We identified confluent signatures, many related to interferon signaling, indicating pathways that may be targeted for therapy. Furthermore, we observed a high (>80%) expression of candidate genes for the different diseases at the target tissue level.
Future research on autoimmune diseases should focus on both the immune system and the target tissues, and on their crosstalk.
When
30 October, 14:00-14:45 (Central European Time)
How to participate
You will receive a link to the webinar after registration deadline.
Speaker
Professor Decio L. Eizirik, ULB Center for Diabetes Research, Medical Faculty, Universite Libre de Bruxelles (BE)
Registration
Registration deadline: 30 October 13:00 (Central European Time)
The seats will be allocated on a first come, first served basis.
Additional information
We record the webinar
Please be aware that we might record the webinar in order to publish it at Danish Diabetes Academy's digital channels.